Unclassified · Medical Literature
[The Lancet Gastroenterology & Hepatology Commission] The role of primary care in response to the global liver disease syndemic: a Lancet Gastroenterology & Hepatology Commission
Abstract
Liver disease causes substantial global morbidity and mortality, with a growing burden from steatotic liver disease driven by alcohol use and metabolic dysfunction, alongside persisting challenges from chronic viral hepatitis. Liver disease burden is unequal between and within countries, with high rates in people with low socioeconomic status and marginalised groups due to increased exposure to risk factors and compounded by reduced access to prevention, diagnosis, and treatment. Liver disease frequently coexists with multimorbidity—including diabetes, cancer, and mental illness—with bidirectional relationships that demand integrated, person-centred pathways of care.