Unclassified · Medical Literature

[Articles] Structural brain changes and clinical outcomes of patients with NMDA receptor encephalitis in Germany: a cross-sectional study

Authors
Stephan Krohn, Guido Cammà, Wei Zhao, Amy Romanello, Katharina Wurdack, Ole Jonas Böken, Sophia Rekers, Friedemann Paul, Harald Prüss, Christopher R Madan, Carsten Finke
Journal
The Lancet Psychiatry
Publication date
2026-09-01
Source
rss_lancet_psy
Original record ID
270248
Summary status
error
Analysis status
error
Original last updated
2026-08-17T07:53:15.000Z

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Abstract

Post-acute NMDAR encephalitis is characterised by systematic alterations of brain morphology. These changes are associated with persistent psychiatric symptoms and memory dysfunction after immunotherapy, highlighting fractal dimensionality as a promising new imaging marker of long-term outcomes. The phenotypic shift in psychiatric symptoms and the persistence of memory dysfunction highlight the importance of structured post-acute care to address long-term affective and cognitive morbidity in patients with NMDAR encephalitis.