Unclassified ยท Medical Literature

[Comment] Genotype-based antimicrobial resistance tests need a new regulatory framework

Authors
Yonatan H Grad, Daniel B Larremore, Marc Lipsitch
Journal
The Lancet Microbe
Publication date
2026-06-09
Source
rss_lancet_mic
Original record ID
270258
Summary status
error
Analysis status
error
Original last updated
2026-08-17T07:57:10.000Z

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Abstract

Antimicrobial resistance (AMR) is eroding the effectiveness of antibiotics and raising the cost of incorrect empirical therapy. Sequence-based diagnostics that infer antimicrobial susceptibility from pathogen genomes promise faster, more tailored prescribing than culture-based susceptibility testing,1 especially for slow-growing pathogens (eg, Mycobacterium tuberculosis), infections for which susceptibility testing is rarely done (eg, Neisseria gonorrhoeae), and common pathogens such as Staphylococcus aureus.