Obstetrics & Gynecology
Laparoscopic surgery has become the mainstream approach for gynecological procedures. However, postoperative pain, particularly visceral pain, remains a major obstacle to achieving enhanced recovery after surgery. Therefore, this study aimed to observe the clinical effects of opi
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This paper aims to evaluate the effects of online pelvic floor muscle training on urinary incontinence frequency, symptom severity, quality of life and adherence across defined female life stages. Urinary incontinence is a significant public health issue affecting women's ph
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This systematic review investigated the effect of protein intake on anthropometric and body composition markers in pre- to postmenopausal women. Understanding these effects may contribute to the development of nutritional strategies to improve body composition and prevent changes
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Polycystic ovary syndrome (PCOS), the most common endocrine disorder in reproductive-aged women, often leads to gestational diabetes mellitus (GDM). This study aimed to systematically evaluate GDM prevalence and its associated factors in PCOS. We searched PubMed, Embase, Web of S
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Richard Horton's Offline1 on the ten lessons for reproductive, maternal, newborn, child, and adolescent health is well judged, but misses the political economy trap that chronic resource scarcity itself creates and sustains.
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In Singapore, cervical cancer screening rates remain suboptimal, with only clinician sampling included in the national screening program. Self-sampling human papillomavirus (HPV) DNA testing might overcome barriers to clinician-based screening and improve uptake. We assessed the
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Acute postprocedural pain remains a major barrier to uterine fibroid embolization (UFE). To assess whether intraarterial dexamethasone reduces postprocedural pain after UFE. This double-blind, placebo-controlled randomized clinical trial was conducted from July 2020 to December 2
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After radical hysterectomy for cervical cancer, postoperative bladder dysfunction is common. This randomized controlled trial evaluated whether adjunctive transcutaneous electrical acupoint stimulation (TEAS) reduces urinary retention. A total of 108 patients were assigned to a c
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Tuberculosis (TB) is an important global health problem, especially for pregnant women, a vulnerable group. This systematic review and meta-analysis was conducted in this group to obtain cumulative results in a collective effort toward the World Health Organization (WHO) End TB S
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Age at menarche is a dynamic indicator of a female's health trajectories. Despite its relevance, the cohesive synthesis of its multifactorial determinants in South Asia is lacking, limiting the targeted public health strategies. This review examines the sociodemographic, nut
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Self-collection models are regarded as a potential strategy to facilitate HPV testing for cervical cancer screening. HPV testing using urine specimens offers certain advantages, including its noninvasiveness. This characteristic has the potential to eliminate discomfort. Concerns
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This study aimed to evaluate the efficacy and safety of Dingjunsheng, a live Lactobacillus preparation, as adjuvant therapy in patients with human papillomavirus (HPV) infection complicated by bacterial vaginosis (BV). A retrospective analysis was conducted on 152 eligible patien
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Human papillomavirus (HPV) is a prevalent sexually transmitted infection that negatively affects women's psychological, social, and sexual well-being worldwide. This study aimed to evaluate the effect of group Acceptance and Commitment Therapy (ACT) counseling on sexual func
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Sexually transmitted infections (STIs) are at a record high in the United States and are a significant health problem for childbearing women. Rates of substance use, particularly cannabis and opioid use, have increased in recent years and are linked to negative health consequence
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Cervical cancer and its precursor lesions are treatable if detected early; however, screening participation for high-risk human papillomavirus infections (hr-HPV) remains low. In 2021, Germany recorded 4,544 new cervical cancer cases and 2,071 related deaths. The HaSCo study eval
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Very few clinical studies have been done to evaluate the potential clinical benefit of utilizing early colposcopy in women with normal Pap smear cytology but positive for high-risk human papillomavirus types other than human papillomavirus 16 or human papillomavirus 18 in a scree
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Gestational diabetes mellitus (GDM) commonly presents as insulin resistance and altered lipid metabolism, with evidence linking vitamin D deficiency to its pathogenesis. In this randomized, double-blind, placebo-controlled trial, 120 pregnant women diagnosed with GDM were assigne
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Clomiphene citrate (CC) is the first-line medication for inducing ovulation in women with polycystic ovary syndrome (PCOS). However, approximately 20% of patients with PCOS are resistant to CC. This study aims to identify reliable baseline predictors of CC resistance in infertile
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Risk-reducing salpingo-oophorectomy (RRSO) is an effective option to prevent ovarian cancer in high-risk individuals, but adverse effects from premature menopause are a barrier to uptake. Interval salpingectomy with delayed oophorectomy (ISDO) may be an effective alternative. To
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Background and objectives Hypothyroidism is the most common thyroid disorder during pregnancy and, if not managed adequately, increases the risk of adverse foeto-maternal outcomes. The present systematic review and meta-analysis was conducted to assess the prevalence of hypothyro
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This study evaluated the effectiveness of synchronous online simulation compared with face-to-face instruction in teaching episiotomy repair skills to midwifery students. It also assessed learning satisfaction and self-confidence. A randomized controlled study was conducted with
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Obese parturients are at increased risk of spinal anesthesia-induced hypotension during cesarean delivery, but optimal prophylactic norepinephrine dosing remains unclear. In this randomized, double-blind, dose-response study, 200 parturients undergoing elective cesarean delivery
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Although reproductive vaccines are essential in swine herd health programs, evidence on their safety across different physiological stages remains limited. This study evaluated the clinical and reproductive safety of Porcilis® EPL in sows and gilts under commercial field conditio
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Women who experience assisted reproductive treatment failure may be at risk of developing sexual dysfunction. This study compared the effects of two different sexual counselling models, EX-PLISSIT and BETTER, on the sexual function of women after an unsuccessful assisted reproduc
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Selected patients with obstructed defecation syndrome (ODS) and concomitant pelvic organ prolapse (POP) may require laparoscopic resection rectopexy (L-RRP) with laparoscopic sacrocolpopexy (L-SCP). This trial compared the safety and efficacy of biologic versus synthetic mesh (BM
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Physiologically based pharmacokinetic (PBPK) modeling is increasingly used to predict infant exposure to medications via breast milk. Existing guidance on reporting of PBPK modeling analyses is unstructured and nonbinding to researchers. We evaluated reporting practices and model
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Acupuncture, a common intervention in traditional Chinese medicine (TCM), has been widely applied for regulating hormonal fluctuations in perimenopausal women. However, the efficacy of various acupuncture modalities is not comprehensively compared. This network meta-analysis (NMA
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To systematically evaluate the evidence on the contraceptive efficacy, cycle control, safety, and selected noncontraceptive effects of estetrol 15 mg/drospirenone 3 mg (E4/DRSP) and to assess certainty of evidence by outcome using the GRADE approach. A systematic review was condu
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Chronic pain following Cesarean section significantly impacts quality of life. Postcesarean pain is often treated with pharmacologic therapies; however, there are no evidence-based guidelines available for refractory pain. The objective of this study is to determine if acupunctur
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Effective postoperative analgesia following cesarean delivery is crucial for maternal recovery. Sufentanil, commonly administered via patient-controlled intravenous analgesia (PCIA), is associated with dose-dependent adverse effects, particularly gastrointestinal disturbances. Ol
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To the Editor Drs Alperin and Artsen provide a thoughtful and balanced review of cesarean delivery on maternal request, emphasizing maternal outcomes, pelvic floor considerations, and short-term neonatal risks. Their discussion highlights the importance of shared decision-making
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In Reply We appreciate the thoughtful letter from Drs Bellanti and Li regarding the effect of cesarean delivery on maternal request on the infant microbiome and immunologic development. We agree that short- and long-term fetal and maternal risks must be carefully considered when
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To investigate the efficacy of glycopyrronium bromide in preventing postoperative nausea and vomiting (PONV) in patients undergoing gynecological hysteroscopic day surgery. This study is a prospective, randomized, double-blind, non-inferiority trial. The non-inferiority margin wa
Open article →Obstetrics & Gynecology
Polycystic ovarian syndrome (PCOS) is by far the most prevalent metabolic disease affecting women during their reproductive life. Obesity is a frequently associated manifestation of polycystic ovary syndrome. Central body fat accumulation has been associated with the production o
Open article →Obstetrics & Gynecology
OBJECTIVES: To (1) estimate the prevalence of pelvic floor symptoms in performing artists and artistic athletes and (2) quantify the impact of symptoms during and outside performance and training. DESIGN: Epidemiology systematic review with meta-analysis. LITERATURE SEARCH: Six d
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Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), used to treat type 2 diabetes and obesity, may improve metabolic health before conception. However, their association to hypertensive disorders of pregnancy (HDP) after periconceptional or early pregnancy exposure remains unk
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To evaluate whether adding milk of magnesia (MOM) to an enhanced recovery after surgery (ERAS) pathway prevents postoperative ileus (POI) and improves postoperative bowel function. This randomized controlled trial at the Gynecology Unit, Siriraj Hospital (Bangkok, Thailand) enrol
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CTRI/2025/06/088470 (https://ctri.nic.in).
Open article →Obstetrics & Gynecology
Diabetes mellitus management requires considerable patient self-efficacy, knowledge, and support for social determinants of health. These needs become particularly acute during pregnancy. Mobile health (mHealth) tools are a promising approach to enhance patient engagement with th
Open article →Obstetrics & Gynecology
Background Lactational mastitis is a common inflammatory condition that can adversely affect maternal well-being and is associated with early cessation of breastfeeding. Although antibiotics and analgesics are widely used in clinical practice, concerns regarding antimicrobial res
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Background Completing continuous maternity care (COCMC) is crucial for preventing morbidity and mortality, but a low proportion of mothers use it. There is a paucity of evidence about the level of COCMC and the associated factors in agro-pastoralist communities. Objective To iden
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