Rheumatology

JAK inhibitor therapy in CANDLE syndrome: a systematic review of clinical outcomes in 46 patients. | ClinicLens

Chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature (CANDLE) syndrome is a rare autosomal recessive autoinflammatory disorder caused by mutations affecting proteasome function. Given the absence of standard therapy, we reviewed the therapeutic pot

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